Author: wildgreenquest@gmail.com

One of the hardest parts of loving a dog is knowing you’ll almost certainly outlive them. But a San Francisco startup is on its way to bringing the first dog longevity drug to market. Loyal, founded by 31-year-old Celine Halioua, has developed LOY-002, a daily pill for senior dogs that targets the metabolic drivers of aging. The company has raised over $150 million and completed the largest clinical trial in veterinary medicine history — 1,300 dogs across 70 clinics — to prove the drug works. The FDA has already signed off on its safety and reasonable expectation of effectiveness, putting…

Willie Simon stood outside the Memphis motel where Rev. Martin Luther King, Jr. was assassinated in 1968, now a museum dedicated to the Civil Rights Movement.Days after the U.S. Supreme Court gutted a key provision of the Voting Rights Act, Simon feared what the decision would mean not just for Black Americans like himself but an entire country where the political guardrails seem to be coming apart.Simon, who leads the Shelby County Democratic Party in Tennessee, said the court’s conservative majority set a precedent that if you’re “not in the in-crowd group, they can just erase us.”By weakening a requirement…

Opinions expressed by Entrepreneur contributors are their own. Key Takeaways The digital industry has traded quality for performance. Since nearly everything can be measured, the temptation to let those numbers stand in for quality is nearly irresistible. A culture of “learned timidity” emerges when data overrides judgment. Teams become skilled at making work that avoids criticism, not work that is genuinely good. Rebuilding a craft culture inside a metrics-driven industry happens through the repeated choice to hold the work to a standard that the data alone cannot confirm. At some point in the last 15 years, the digital industry made…

A luxury cruise ship is currently being held off the coast of West Africa after a suspected outbreak of hantavirus—a rare infectious disease typically carried by rodents—killed three passengers and infected three others.  The World Health Organization (WHO) shared the news of the suspected outbreak in a post to X. According to the organization, one case of hantavirus on the ship, MV Hondius, had been confirmed through laboratory testing, and there are five additional suspected cases.Of those six affected individuals, three have died and one is currently in intensive care in South Africa. According to an official update from Dutch company…

Opinions expressed by Entrepreneur contributors are their own. Key Takeaways The most effective leaders approach regret with humility. They use it to make better future decisions, sharpen their judgment and improve their leadership skills. Learning from regret requires discipline — soliciting tough feedback, owning mistakes and turning failures into learning opportunities. Even the most successful CEOs can point to decisions they wish they’d made differently. What sets great leaders apart isn’t the absence of mistakes; it’s how they respond to them.Throughout my career, I’ve noticed that the most effective leaders approach regret with humility, using it as a tool to…

The music industry has seen disruption before. Vinyl gave way to cassettes, CDs to Napster, downloads to streaming. Each shift rewired how the music industry distributes and monetizes songs but did not change what music fundamentally is or the fact that humans have always created it. Artificial intelligence doesn’t just change how music moves. It challenges who owns it and who gets paid for it. The real threat of AI isn’t that it can make songs. It’s that it reveals how fragile the music industry is. For years, artists have operated inside a system where millions of streams translate into fractions of…

Opinions expressed by Entrepreneur contributors are their own. The collapse of Silicon Valley Bank was an existential crisis for founders like me — one that came out of nowhere and had nothing to do with the strength of our businesses. Overnight, something as basic as access to our own capital was thrown into question.It exposed a hard truth: much of the startup ecosystem was built on assumptions that had never been truly tested under pressure. Founders were suddenly forced to confront questions most had never seriously considered — how secure their banking relationships really were, how resilient their capital structure…

You might remember ZenBooths—Amazon’s contribution to corporate well-being. These were booths installed in the middle of warehouses, equipped with a fan, a potted plant, and a monitor playing meditation videos. The company called them mindful practice rooms. Employees called them despair chambers. The internet called them coffins for workers—workers who, incidentally, didn’t even have time to use the bathroom because of crushing productivity demands.ZenBooths are, I think, a fitting metaphor for modern corporate wellness. According to Gallup, employee engagement dropped to 20% in 2025—the lowest it’s been since the COVID-19 lockdowns. Companies are pouring money into all kinds of initiatives,…

GameStop is playing the biggest game of its life: a bid to buy eBay, a company nearly four times its size, according to The Wall Street Journal. The videogame retailer and meme stock, led by billionaire Chewy co-founder Ryan Cohen, is preparing a takeover offer for the $46 billion online marketplace. GameStop’s market cap sits at just $12 billion, meaning Cohen would need massive debt financing to pull off the deal. The two companies may seem like odd bedfellows, but there is strategic overlap. Both companies have pivoted hard into collectibles — trading cards, sports memorabilia, Pokémon — and eBay’s…

Published May 4, 2026 05:07PMFor the real-life heroes who save lives and aid our communities when they need it most, getting there is half the battle. For decades, Defender’s legendary capability has empowered humanitarian efforts, helping aid workers navigate the rural roads, flood zones, wilderness areas, and beyond to deliver vital resources like medical attention, rescue, or emergency food. In 2021, Defender added to that global legacy with the launch of the Defender Service Awards Presented by Chase, a program that supports mission-driven nonprofits that are out there on the ground, making communities safer, healthier, and better for the people…