SAINT HELENA ISLAND – APRIL 24: A view of the Dutch-flagged vessel MV Hondius is seen navigating the Atlantic Ocean near Saint Helena Island on April 24, 2026. ages)
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Three deaths and nine reported cases of Hantavirus have been associated with an outbreak on the cruise ship MV Hondius, according to the European Center for Disease Prevention and Control. The cases and deaths have been linked to the Andes strain, the only strain of hantavirus that can spread person-to-person.
These cases have understandably caused concern and consternation for many Americans. The experience from the COVID-19 pandemic can offer important lessons for how the United States can respond in order to prevent fear, confusion and unnecessary escalation while ensuring the country remains ready if risks evolve.
Here are several lessons that could prove beneficial.
Communication And Transparency Matter
One of the biggest challenges during COVID-19 was inconsistent messaging, particularly from federal government officials and healthcare providers on topics such as masks and social distancing. This shifting and discrepant guidance undermined public trust and led to confusion among Americans.
With the Andes hantavirus, any uncertainty should be explained clearly and openly to the American public to build trust and confidence in public health. Although the CDC has been actively posting updates on X, there has been a scarcity of public health debriefings, announcements and press conferences from the department of Health and Human Services providing updates to the general public. The American people have many questions about what to expect, what their general risk is and if they will be ever exposed to the virus. Clear consistent communication may prove more important than perfect information.
Surveillance And Contact Tracing Must Start Immediately
Early containment tools work best when deployed early. As occurred for COVID-19, implementation of isolation and quarantine measures for those infected occurred too late, leading to rapid spread of disease.
Although the Andes strain does not spread nearly as efficiently or effectively as COVID-19, international coordination and careful monitoring of close contacts and those exposed will be critical since the Andes strain can spread person-to-person. This surveillance will allow the interruption of transmission before cases can spread.
Isolation Strategies Should Be Targeted, Not Broad
COVID-19 is an airborne virus that spreads easily through aerosol viral particles. The Andes strain of hantavirus is different, and usually spreads through prolonged close contact. Given widespread community transmission is not likely with the Andes strain, the U.S. response should focus on targeted isolation of confirmed cases and monitoring of high-risk contacts rather than restrictions that can ignite fear and panic.
The World Health Organization has offered flexibility in their approach to those exposed on the cruise ship. They have recommended a 42-day quarantine or active monitoring at home which would include daily symptom tests. This type of precision public health protocol prevents unnecessary societal disruptions while maintaining safety.
Science Should Drive Public Health Decisions
COVID-19 demonstrated that public health measures succeed only when Americans trust institutions delivering guidance.
During the pandemic, politicization of vaccines and confusing messaging from politicians weakened compliance with vaccines during the pandemic. Vaccines save lives, and COVID-19 vaccines developed through Operation Warp Speed are credited for saving over a million American lives.
For hantavirus response efforts, messaging must remain science-driven and devoid of political influence. If politicians and health officials follow evidence-based guidelines, trust will develop to help safeguard the health of all Americans.
The United States holds the keys to ensure the Andes strain is successfully contained with minimal risk to the general population. Transparent evidence-based communication with proactive public health surveillance should form the cornerstone of the U.S. response.
